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Article

Aromatic hydrocarbon receptor polymorphism: development of new methods to correlate genotype with phenotype.

Environmental health perspectives - 1 Jul 1998

Maier A, Micka J, Miller K, Denko T, Chang C Y, Nebert D W, Alvaro Puga

Abstract excerpt

Differential CYP1A1 inducibility, reflecting variations in aromatic hydrocarbon receptor (AHR) affinity among inbred mouse strains, is an important determinant of environmental toxicity. We took advantage of the Ahr polymorphism in C57BL/6 and DBA/2 mice to develop an oligonucleotide-hybridizatio...

Topics

Animals
Cytochrome P-450 CYP1A1
Enzyme Induction
Genotype
Humans
Hydrocarbons, Aromatic
In Situ Hybridization
Ligands
Mice
Phenotype
Plasmids
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Aryl Hydrocarbon

Saccharomyces cerevisiae

beta-Galactosidase

Source

Open in PubMed Open full text

Identifiers

PMID: 9637800
DOI: 10.1289/ehp.106-1533118
PMCID: PMC1533118

Genes

AHR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9637800-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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