Molecular determinants of the prothrombogenic phenotype assumed by inflamed colonic venules.

doi:10.1152/ajpgi.00371.2004

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Article

Molecular determinants of the prothrombogenic phenotype assumed by inflamed colonic venules.

American journal of physiology. Gastrointestinal and liver physiology - 1 May 2005

Mori Mikiji, Salter James W, Vowinkel Thorsten, Krieglstein Christian F, Stokes Karen Y, Granger D Neil

Abstract excerpt

Although platelets have been implicated in the pathogenesis of human inflammatory bowel diseases, little is known about the magnitude of platelet accumulation in the inflamed bowel, what regulates this process, and its relevance to the overall inflammatory response. In this study, intravital vide...

Topics

Animals
Anticoagulants
Blood Platelets
Capillary Permeability
Cell Adhesion
Colitis
Colon
Dextran Sulfate
Gene Expression
Inflammation
Leukocytes
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Membrane Glycoproteins

Mice

Mice, Inbred C57BL

Mice, Knockout

P-Selectin

Phenotype

Source

Open in PubMed

Identifiers

PMID: 15550557
DOI: 10.1152/ajpgi.00371.2004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-15550557-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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