Article
Analysis of immunoglobulin genes in splenic marginal zone lymphoma suggests ongoing mutation.
Human pathology - 1 Jun 1998
Dunn-Walters D K, Boursier L, Spencer J, Isaacson P G
Abstract excerpt
Splenic marginal zone lymphoma (SMZL) is a low-grade primary splenic B cell lymphoma, originally thought to be related to splenic marginal zone B cells. Later studies showed that SMZL sometimes may be accompanied by villous lymphocytes in the peripheral blood, a condition previously characterized...
Topics
- Aged
- Base Sequence
- DNA Mutational Analysis
- DNA Primers
- DNA, Neoplasm
- Female
- Genes, Immunoglobulin
- Humans
- Immunoglobulin Heavy Chains
- Immunoglobulin Variable Region
- Immunohistochemistry
- Lymphoma, B-Cell
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Splenic Neoplasms