Article
[Molecular analysis of immunoglobulin genes in the tumor B cells in splenic marginal zone lymphoma].
Terapevticheskii arkhiv - 1 Jan 2015
Julakyan U L, Biderman B V, Gemdzhian E G, Sudarikov A B, Savchenko V G
Abstract excerpt
AIM: To determine the immunoglobulin variable heavy chain (gVH) genes and their somatic mutations and to compare these data with the clinical and laboratory parameters of patients and the outcomes of the disease. SUBJECTS AND METHODS: The investigation enrolled 24 patients (9 men and 15 women whose age was 32 to 77 years (median age, 60 years) with splenic marginal zone B-cell lymphoma (SMZBCL). The latter was...
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