Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutation of the PTEN tumor suppressor gene in endometrial hyperplasias.

Cancer research - 15 Jun 1998

Maxwell G L, Risinger J I, Gumbs C, Shaw H, Bentley R C, Barrett J C, Berchuck A, Futreal P A

Abstract excerpt

Mutation and deletion of the PTEN tumor suppressor gene occurs in about 40% of endometrial carcinomas. The purpose of this study was to determine whether PTEN mutations also are present in endometrial hyperplasias, which are premalignant precursors of invasive endometrial adenocarcinomas. Genomic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to PTEN gene
Share to Genes, Tumor Suppressor
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Proteins

Share to Phosphoric Monoester Hydrolases

Share to Polymerase Chain Reaction

Share to Protein Tyrosine Phosphatases

Share to Tumor Suppressor Proteins

Source

Identifiers

PMID: 9635567

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9635567-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutation of the PTEN tumor suppressor gene in endometrial hyperplasias.PMID 9635567Read ↗

Mutational analysis of the PTEN gene in endometrial carcinoma and hyperplasia.Semantic proximity Read ↗

Assessment of the quality and frequency of mutations occurrence in PTEN gene in endometrial carcinomas and hyperplasias.Semantic proximity Read ↗

Altered PTEN Expression as a Diagnostic Marker for the Earliest Endometrial PrecancersSemantic proximity Read ↗

Clonal analysis and mutations in the PTEN and the K-ras genes in endometrial hyperplasia.Semantic proximity Read ↗

PTEN sequence analysis in endometrial hyperplasia and endometrial carcinoma in Slovak women.Semantic proximity Read ↗

PTEN mutation in endometrial cancers is associated with favorable clinical and pathologic characteristics.Semantic proximity Read ↗

PTEN mutations as predictive marker for the high-grade endometrial cancer development in slovak women.Semantic proximity Read ↗

Distinct sets of gene alterations in endometrial carcinoma implicate alternate modes of tumorigenesis.Semantic proximity Read ↗

Genetic derangements in the tumor suppressor gene PTEN in endometrial precancers as prognostic markers for cancer development: a population-based study from northern Norway with long-term follow-up.Semantic proximity Read ↗

Genetic alterations in endometrial hyperplasia and cancer.Semantic proximity Read ↗

Molecular pathology of endometrial hyperplasia and carcinoma.Semantic proximity Read ↗

Loss of PTEN expression is associated with metastatic disease in patients with endometrial carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.