Article
Genetic alterations in endometrial hyperplasia and cancer.
Cancer letters - 25 Jan 2002
Fabjani Gerhild, Kucera Elisabeth, Schuster Eva, Minai-Pour Michael, Czerwenka Klaus, Sliutz Gerhard, Leodolter Sepp, Reiner Angelika, Zeillinger Robert
Abstract excerpt
Putative precursors of endometrial cancer such as complex endometrial hyperplasia with atypia have been described to be monoclonal and considered to be genetically related. In order to identify a genetic marker that could serve as a putative predictor of endometrial cancer we analyzed 14 endometrial hyperplasia and 29 endometrial cancer samples for instabilities and loss of heterozygosity (LOH) in microsatellite...
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