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Article

PTEN sequence analysis in endometrial hyperplasia and endometrial carcinoma in Slovak women.

Analytical cellular pathology (Amsterdam) - 1 Jan 2015

Gbelcová H, Bakeš P, Priščáková P, Šišovský V, Hojsíková I, Straka Ľ, Konečný M, Markus J, D'Acunto C W, Ruml T, Böhmer D, Danihel Ľ, Repiská V

Abstract excerpt

Phosphatase and tensin homolog (PTEN) is a protein that acts as a tumor suppressor by dephosphorylating the lipid second messenger phosphatidylinositol 3,4,5-trisphosphate. Loss of PTEN function has been implicated in the pathogenesis of a number of different tumors, particularly endometrial carcinoma (ECa). ECa is the most common neoplasia of the female genital tract. Our study evaluates an association between...

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Source

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Identifiers

PMID: 26114084
DOI: 10.1155/2015/746856
PMCID: PMC4465682

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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