Article
Distinct sets of gene alterations in endometrial carcinoma implicate alternate modes of tumorigenesis.
Cancer - 1 May 2002
Koul Anjila, Willén Roger, Bendahl Pär-Ola, Nilbert Mef, Borg Ake
Abstract excerpt
BACKGROUND: Endometrial carcinomas seem to carry a different prognosis depending on the presence or absence of concomitant complex atypical hyperplasia (hyperplasia). The molecular genetic profile of these two pathogenetic types, based on the genes reportedly mutated in these cancers, remains to be defined. Although microsatellite inability is reported in approximately 25% of endometrial carcinomas, its relation...
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