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Article

Adenovirus targeted to heparan-containing receptors increases its gene delivery efficiency to multiple cell types.

Nature biotechnology - 1 Nov 1996

Wickham T J, Roelvink P W, Brough D E, Kovesdi I

Abstract excerpt

Adenovirus (Ad) is used as a vector for gene delivery in therapies involving genetic disease, vascular disease, and cancer. The first step for efficient gene transfer is effective virus binding to the target cells. We have found that Ad-mediated gene delivery to multiple cell types is much less e...

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PMID: 9634823
DOI: 10.1038/nbt1196-1570

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-9634823-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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