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Article

Protease inhibitor resistance update: where are we now?

AIDS patient care and STDs - 1 Apr 2008

Kim Rose, Baxter John D

Abstract excerpt

The introduction of protease inhibitors (PIs) and highly active antiretroviral therapy in the mid-1990s dramatically altered the treatment of HIV infection, enabling suppression of viral replication to undetectable levels and preventing disease progression. Most PIs present a strong barrier against viral resistance; the accumulation of multiple mutations is often required to produce resistance. However, there is...

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Identifiers

PMID: 18422460
DOI: 10.1089/apc.2007.0099

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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