The functional significance of multimerization in ion channels.

doi:10.1016/s0959-440x(98)80036-5

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Article

The functional significance of multimerization in ion channels.

Current opinion in structural biology - 1 Apr 1998

Tierney M L, Stowell M H

Abstract excerpt

Recently, the allosteric behavior of ion channels has been investigated by recording the individual steps leading to the complete activation of a cyclic nucleotide-gated ion channel. This information, in combination with recent studies on nicotinic acetylcholine receptor mutants, necessitates a m...

Topics

Allosteric Site
Animals
Humans
Ion Channels
Models, Biological
Mutation
Nucleotides, Cyclic
Protein Conformation
Receptors, Nicotinic

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