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Article

Potentiation of acetylcholine receptors by divalent cations.

Molecular pharmacology - 1 Jul 2006

Lindstrom Jon

Abstract excerpt

Divalent cations promote activation of several nicotinic acetylcholine receptor (AChR) subtypes, presumably by lowering the energetic barrier between open and closed conformations. In wild-type alpha7 AChRs, binding of calcium to a particular part of the extracellular domain is required for potentiating activation. McLaughlin et al. (p. 16) tested the hypothesis that movements involved in agonist activation and...

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Source

Identifiers

PMID: 16641314
DOI: 10.1124/mol.106.025767

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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