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Article

Immunobiological studies on experimental visceral Leishmaniasis. V. The I-A(Bm12) mutation specifies resistance to infection.

Scandinavian journal of immunology - 1 May 1998

Sen E, Roy S

Abstract excerpt

The I-A(Bm12) mutation of the I-A beta subunit converted Leishmania donovani-susceptible C57BL/6 (B6) mice into the relatively resistant B6C-H-2 Bm12 (Bm12) strain. The relative resistance was reflected not only in the reduced splenic and hepatic parasite burden in Bm12 (compared with B6) but also by the ability of Bm12 mice to mount a T-cell proliferative response to parasite antigens. Assay of antileishmanial...

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Identifiers

PMID: 9627126
DOI: 10.1046/j.1365-3083.1998.00320.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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