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Article

Germ-line deletion involving the INK4 locus in familial proneness to melanoma and nervous system tumors.

Cancer research - 1 Jun 1998

Bahuau M, Vidaud D, Jenkins R B, Bièche I, Kimmel D W, Assouline B, Smith J S, Alderete B, Cayuela J M, Harpey J P, Caille B, Vidaud M

Abstract excerpt

Joint predisposition to malignant melanoma and nervous system tumors (NSTs) is a puzzle. Several melanoma susceptibility genes have been identified, including p16, a clustered tumor suppressor. However, the molecular bases of inherited proclivity to NSTs in the absence of a recognizable genetic syndrome are unknown. We analyzed two families with joint proneness to melanoma and NSTs in view of genetic linkage and...

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PMID: 9622062

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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