Article
Alterations in CDKN2A locus as potential indicator of melanoma predisposition in relatives of non-familial melanoma cases.
Croatian medical journal - 1 Aug 2003
Levanat Sonja, Situm Mirna, Crnić Ivana, Marasović Dujomir, Puizina-Ivić Neira, Pokupcić Nikola, Musani Vesna, Komar Arijana, Kubat Milovan, Furac Ivana, Karija-Vlahović Monika, Krizanac Simun
Abstract excerpt
AIM: To examine constitutional alterations of CDKN2A/p16INK4A locus as a potential indicator of melanoma predisposition among the first-degree relatives of patients with malignant melanoma. METHOD: The study included eight families with a single member affected with melanoma. Members of the families were screened for allelic cosegregation with 9p21 region polymorphic markers IFNA, D9S126, and D9S104. The...
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