Article
Mutations of the CDKN2/p16INK4 gene in Australian melanoma kindreds.
Human molecular genetics - 1 Oct 1995
Walker G J, Hussussian C J, Flores J F, Glendening J M, Haluska F G, Dracopoli N C, Hayward N K, Fountain J W
Abstract excerpt
The cyclin dependent kinase inhibitor 2 (CDKN2) gene on chromosome 9p21 is potentially involved in the genesis of many cancers and is currently under intense investigation as a possible melanoma susceptibility locus. We have analyzed 18 Australian melanoma kindreds for mutations within the coding and neighboring splice junction portions of the CDKN2 gene. In seven kindreds (including our six largest), CDKN2...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
