Mutations of the CDKN2/p16INK4 gene in Australian melanoma kindreds.

doi:10.1093/hmg/4.10.1845

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Article

Mutations of the CDKN2/p16INK4 gene in Australian melanoma kindreds.

Human molecular genetics - 1 Oct 1995

Walker G J, Hussussian C J, Flores J F, Glendening J M, Haluska F G, Dracopoli N C, Hayward N K, Fountain J W

Abstract excerpt

The cyclin dependent kinase inhibitor 2 (CDKN2) gene on chromosome 9p21 is potentially involved in the genesis of many cancers and is currently under intense investigation as a possible melanoma susceptibility locus. We have analyzed 18 Australian melanoma kindreds for mutations within the coding...

Topics

Australia
Base Sequence
Carrier Proteins
Chromosome Mapping
Chromosomes, Human, Pair 9
Cyclin-Dependent Kinase Inhibitor p16
DNA Primers
Enzyme Inhibitors
Exons
Family
Female
Genes, Tumor Suppressor
Humans
Male
Melanoma
Molecular Sequence Data
Multigene Family
Mutation

Source

Open in PubMed

Identifiers

PMID: 8595405
DOI: 10.1093/hmg/4.10.1845

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8595405-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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