Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Host mutations (miaA and rpsL) reduce tetracycline resistance mediated by Tet(O) and Tet(M).

Antimicrobial agents and chemotherapy - 1 Jan 1998

Taylor D E, Trieber C A, Trescher G, Bekkering M

Abstract excerpt

The effects of mutations in host genes on tetracycline resistance mediated by the Tet(O) and Tet(M) ribosomal protection proteins, which originated in Campylobacter spp. and Streptococcus spp., respectively, were investigated by using mutants of Salmonella typhimurium and Escherichia coli. The miaA, miaB, and miaAB double mutants of S. typhimurium specify enzymes for tRNA modification at the adenosine at position...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Bacterial Proteins
Share to Carrier Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Escherichia coli

Share to Escherichia coli Proteins

Share to Microbial Sensitivity Tests

Share to Mutation

Share to Salmonella typhimurium

Source

Open in PubMed Open full text

Identifiers

PMID: 9449261
DOI: 10.1128/AAC.42.1.59
PMCID: PMC105456

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Host mutations (miaA and rpsL) reduce tetracycline resistance mediated by Tet(O) and Tet(M).PMID 9449261Read ↗

The ms2io6A37 modification of tRNA in Salmonella typhimurium regulates growth on citric acid cycle intermediates.Semantic proximity Read ↗

Three modifications in the D and T arms of tRNA influence translation in Escherichia coli and expression of virulence genes in Shigella flexneri.Semantic proximity Read ↗

tRNA modification activity is necessary for Tet(M)-mediated tetracycline resistance.Semantic proximity Read ↗

The contribution of a novel ribosomal S12 mutation to aminoglycoside resistance of Escherichia coli mutants.Semantic proximity Read ↗

The methylthio group (ms2) of N6-(4-hydroxyisopentenyl)-2-methylthioadenosine (ms2io6A) present next to the anticodon contributes to the decoding efficiency of the tRNA.Semantic proximity Read ↗

Mutations in the bacterial ribosomal protein l3 and their association with antibiotic resistance.Semantic proximity Read ↗

Structural alterations of the tRNA(m1G37)methyltransferase from Salmonella typhimurium affect tRNA substrate specificity.Semantic proximity Read ↗

Molecular determinants of microbial resistance to thiopeptide antibiotics.Semantic proximity Read ↗

Novel ribosomal mutations affecting translational accuracy, antibiotic resistance and virulence of Salmonella typhimurium.Semantic proximity Read ↗

The i6A37 tRNA modification is essential for proper decoding of UUX-Leucine codons during rpoS and iraP translation.Semantic proximity Read ↗

Isolation of spectinomycin resistance mutations in the 16S rRNA of Salmonella enterica serovar Typhimurium and expression in Escherichia coli and Salmonella.Semantic proximity Read ↗

Three modified nucleosides present in the anticodon stem and loop influence the in vivo aa-tRNA selection in a tRNA-dependent manner.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.