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Article

De-phosphorylation of MyoD is linking nerve-evoked activity to fast myosin heavy chain expression in rodent adult skeletal muscle.

The Journal of physiology - 15 Oct 2007

Ekmark Merete, Rana Zaheer Ahmad, Stewart Greg, Hardie D Grahame, Gundersen Kristian

Abstract excerpt

Elucidating the molecular pathways linking electrical activity to gene expression is necessary for understanding the effects of exercise on muscle. Fast muscles express higher levels of MyoD and lower levels of myogenin than slow muscles, and we have previously linked myogenin to expression of oxidative enzymes. We here report that in slow muscles, compared with fast, 6 times as much of the MyoD is in an inactive...

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Identifiers

PMID: 17761773
DOI: 10.1113/jphysiol.2007.141457
PMCID: PMC2277165

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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