A stochastic model of cellular transformation and its relevance to chemical carcinogenesis.

doi:10.1016/s0025-5564(97)10017-7

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Article

A stochastic model of cellular transformation and its relevance to chemical carcinogenesis.

Mathematical biosciences - 1 Apr 1998

Alfano F D

Abstract excerpt

A mathematical model is presented which determines the relationship of cellular mutation to cellular survival and transformation. The basis for this model is the hypothesis that the entropy associated with changes of genotype are linearly proportional to the entropy associated with changes in phe...

Topics

Animals
Carcinogens
Cell Survival
Cell Transformation, Neoplastic
Humans
Mathematics
Models, Biological
Mutation
Stochastic Processes

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