Article
Chemical kinetic mechanistic models to investigate cancer biology and impact cancer medicine.
Physical biology - 1 Apr 2013
Stites Edward C
Abstract excerpt
Traditional experimental biology has provided a mechanistic understanding of cancer in which the malignancy develops through the acquisition of mutations that disrupt cellular processes. Several drugs developed to target such mutations have now demonstrated clinical value. These advances are unequivocal testaments to the value of traditional cellular and molecular biology. However, several features of cancer may...
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