Article
[Stochastic phenomena and the tumoral process].
Medecine sciences : M/S - 1 Jan 2000
Capp Jean-Pascal
Abstract excerpt
In the reductionist perspective, genetic modifications are considered to initiate cancer. Their appearance is a stochastic phenomenon, but there are some biases linked to DNA sequence or exposure to mutagenic agents for instance. Cancer genome sequencing has shown a high inter- and intra-tumoral heterogeneity, sometimes questioning the genetic origin of cancer. Other stochastic processes are also studied in...
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