Article
Expression of transforming growth factor beta receptors in normal human colon and sporadic adenocarcinomas.
Gastroenterology - 1 Jun 1998
Eskinazi R, Resibois A, Svoboda M, Peny M O, Adler M, Robberecht P, Van Laethem J L
Abstract excerpt
BACKGROUND & AIMS: An absence or a presence of mutated transforming growth factor (TGF)-beta receptors is a possible hypothesis explaining the resistance of cancer cells to the growth-inhibitory effect of TGF-beta. Mutations involving microsatellite-like regions of the type II TGF-beta receptor have been described in subgroups of colorectal cancers. The aim of this study was to investigate the expression and...
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