Article
Regulation of amiloride-sensitive sodium absorption in murine airway epithelium by C-type natriuretic peptide.
The American journal of physiology - 1 Jun 1998
Kelley T J, Cotton C U, Drumm M L
Abstract excerpt
We have previously shown that C-type natriuretic peptide (CNP), a guanylate cyclase agonist, can stimulate cystic fibrosis transmembrane conductance regulator (CFTR)-mediated chloride secretion in murine airway epithelial cells via protein kinase (PK) A activation through the inhibition of cGMP-inhibited phosphodiesterases. In this paper, we show that CNP is also capable of reducing amiloride-sensitive sodium...
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