Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tumor necrosis factor alpha production by oral leukocytes: influence of tumor necrosis factor genotype.

Journal of periodontology - 1 Apr 1998

Galbraith G M, Steed R B, Sanders J J, Pandey J P

Abstract excerpt

Tumor necrosis factor alpha (TNF-alpha) is a proinflammatory cytokine that is thought to play a role in the pathogenesis of periodontal disease. TNF-alpha production is regulated by many factors, including certain alleles of TNF gene polymorphisms. In the present study, TNF genotypes of 3 bi-allelic polymorphisms were determined in 32 Caucasian patients with adult periodontitis and 32 orally-healthy matched...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Frequency
Share to Alleles
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chi-Square Distribution

Share to TNF gene

Share to Genotype

Share to Polymorphism, Restriction Fragment Length

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 9609372
DOI: 10.1902/jop.1998.69.4.428

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tumor necrosis factor alpha production by oral leukocytes: influence of tumor necrosis factor genotype.PMID 9609372Read ↗

Polymorphic cytokine genotypes as markers of disease severity in adult periodontitis.Semantic proximity Read ↗

TNF-α gene promoter polymorphisms contribute to periodontitis susceptibility: evidence from 46 studies.Semantic proximity Read ↗

Tumor necrosis factor-alpha gene polymorphisms in relation to periodontitis.Semantic proximity Read ↗

Tumor necrosis factor-alpha gene (TNF-alpha) -1031/-863, -857 single-nucleotide polymorphisms (SNPs) are associated with severe adult periodontitis in Japanese.Semantic proximity Read ↗

Association of TNF-α-308G/A, -238G/A, -863C/A, -1031T/C, -857C/T polymorphisms with periodontitis susceptibility: Evidence from a meta-analysis of 52 studies.Semantic proximity Read ↗

Association Between Apical Periodontitis and TNF-α -308 G>A Gene Polymorphism: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

The -308 polymorphism in the promoter region of the tumor necrosis factor-alpha (TNF-alpha) gene and ex vivo lipopolysaccharide-induced TNF-alpha expression in patients with aggressive periodontitis and/or type 1 diabetes mellitus.Semantic proximity Read ↗

Tumor necrosis factor-α G-308A (rs1800629) polymorphism and aggressive periodontitis susceptibility: a meta-analysis of 16 case-control studies.Semantic proximity Read ↗

Tumor Necrosis Factor Alpha -308 G/A Single-Nucleotide Polymorphism and Apical Periodontitis: An Updated Systematic Review and Meta-analysis.Semantic proximity Read ↗

Lack of association between the TNF alpha G -308 A promoter polymorphism and periodontal disease.Semantic proximity Read ↗

Four tumor necrosis factor alpha genes polymorphisms and periodontitis risk in a Chinese population.Semantic proximity Read ↗

Tumor necrosis factor-alpha -308G/A single nucleotide polymorphism and red-complex periodontopathogens are independently associated with increased levels of tumor necrosis factor-alpha in diseased periodontal tissues.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.