Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lack of association between the TNF alpha G -308 A promoter polymorphism and periodontal disease.

Journal of clinical periodontology - 1 Jun 2004

Folwaczny Matthias, Glas Jürgen, Török Helga-Paula, Mende Monika, Folwaczny Christian

Abstract excerpt

BACKGROUND: Immunorelevant gene polymorphisms might influence the susceptibility for periodontal disease. The present study assessed the frequency of a promoter polymorphism (-308G-to-A) of the tumour necrosis factor (TNF)alpha gene in patients with periodontitis and controls. METHODS: Eighty-one patients with generalized chronic periodontitis and 80 healthy controls were genotyped for the -308 polymorphism of...

Topics

Adenine
Adult
Aged
Alleles
Chronic Disease
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype
Guanine
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Periodontitis

Polymorphism, Genetic

Promoter Regions, Genetic

Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 15142214
DOI: 10.1111/j.1600-051x.2004.00499.x

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-15142214-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lack of association between the TNF alpha G -308 A promoter polymorphism and periodontal disease.PMID 15142214Read ↗

Lack of association between the TNF-alpha -308 (G/A) genetic polymorphism and periodontal disease in Brazilians.Semantic proximity Read ↗

Tumor necrosis factor-alpha gene polymorphisms in relation to periodontitis.Semantic proximity Read ↗

Genetic markers of tumour necrosis factor alpha in aggressive and chronic periodontitis.Semantic proximity Read ↗

Association of TNF-α-308G/A, -238G/A, -863C/A, -1031T/C, -857C/T polymorphisms with periodontitis susceptibility: Evidence from a meta-analysis of 52 studies.Semantic proximity Read ↗

TNF-α gene promoter polymorphisms contribute to periodontitis susceptibility: evidence from 46 studies.Semantic proximity Read ↗

Lack of association between IL-10 -1082G/A polymorphism and chronic periodontal disease in adults.Semantic proximity Read ↗

[Association of TNFA-308 gene polymorphisms with susceptibility to chronic periodontitis in Chinese patients].Semantic proximity Read ↗

Association of Tumour Necrosis Factor-Alpha with Periodontitis Patients in North Indian Population.Semantic proximity Read ↗

Association Between Apical Periodontitis and TNF-α -308 G>A Gene Polymorphism: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Genetic polymorphism of the tumor necrosis factor (TNF)-alpha promoter region in families with localized early-onset periodontitis.Semantic proximity Read ↗

Analysis of IL-1A(-889) and TNFA(-308) gene polymorphism in Brazilian patients with generalized aggressive periodontitis.Semantic proximity Read ↗

Association between tumor necrosis factor-α promoter -308 A/G, -238 A/G, interleukin-6 -174 G/C and -572 G/C polymorphisms and periodontal disease: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.