Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TNF-α gene promoter polymorphisms contribute to periodontitis susceptibility: evidence from 46 studies.

Journal of clinical periodontology - 1 Aug 2014

Ding Cheng, Ji Xiaowei, Chen Xing, Xu Yan, Zhong Liangjun

Abstract excerpt

AIM: Tumour necrosis factor-alpha (TNF-α) plays a critical role in the pathogenesis of periodontal disease. TNF-α gene polymorphisms can influence the TNF-α production. Many studies have focused the association between TNF-α gene promoter polymorphisms and periodontitis risk, but these results are still controversial. MATERIALS AND METHODS: A meta-analysis was performed to assess the effect of TNF-α -308G/A...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenine
Share to Cytosine
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Guanine

Share to Periodontitis

Share to Polymorphism, Genetic

Share to Promoter Regions, Genetic

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 24905365
DOI: 10.1111/jcpe.12279

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TNF-α gene promoter polymorphisms contribute to periodontitis susceptibility: evidence from 46 studies.PMID 24905365Read ↗

Association of TNF-α-308G/A, -238G/A, -863C/A, -1031T/C, -857C/T polymorphisms with periodontitis susceptibility: Evidence from a meta-analysis of 52 studies.Semantic proximity Read ↗

Tumor necrosis factor-α G-308A (rs1800629) polymorphism and aggressive periodontitis susceptibility: a meta-analysis of 16 case-control studies.Semantic proximity Read ↗

TNF-α polymorphisms might influence predisposition to periodontitis: A meta-analysis.Semantic proximity Read ↗

Association of tumor necrosis factor-α (TNF-α) gene promoter polymorphisms with aggressive and chronic periodontitis in the eastern Indian population.Semantic proximity Read ↗

Four tumor necrosis factor alpha genes polymorphisms and periodontitis risk in a Chinese population.Semantic proximity Read ↗

Association between tumor necrosis factor-α promoter -308 A/G, -238 A/G, interleukin-6 -174 G/C and -572 G/C polymorphisms and periodontal disease: a meta-analysis.Semantic proximity Read ↗

Association between TNF-α G-308A (rs1800629) polymorphism and susceptibility to chronic periodontitis and type 2 diabetes mellitus: A meta-analysis.Semantic proximity Read ↗

Association Between Tumor Necrosis Factor-α (G-308A) Polymorphism and Chronic Periodontitis, Aggressive Periodontitis, and Peri-implantitis: A Meta-analysis.Semantic proximity Read ↗

Detection of association between periodontitis and polymorphisms of IL-1β + 3954 and TNF-α -863 in the Korean population after controlling for confounding risk factors.Semantic proximity Read ↗

Tumor Necrosis Factor Alpha -308 G/A Single-Nucleotide Polymorphism and Apical Periodontitis: An Updated Systematic Review and Meta-analysis.Semantic proximity Read ↗

Association of Tumour Necrosis Factor-Alpha with Periodontitis Patients in North Indian Population.Semantic proximity Read ↗

Association Between Apical Periodontitis and TNF-α -308 G>A Gene Polymorphism: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.