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Article

Polymorphic cytokine genotypes as markers of disease severity in adult periodontitis.

Journal of clinical periodontology - 1 Nov 1999

Galbraith G M, Hendley T M, Sanders J J, Palesch Y, Pandey J P

Abstract excerpt

The distributions of the bi-allelic interleukin-1beta+3953 and tumor necrosis factor-alpha-308 genotypes were determined in 20 patients with advanced adult periodontitis, 20 patients with plaque associated gingivitis, and 45 referent population subjects. A significant increase in IL-1beta+3953 allele 2 frequency was found in patients with advanced periodontitis compared to referent subjects (the Fisher exact...

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PMID: 10589805
DOI: 10.1034/j.1600-051x.1999.t01-1-261101.x

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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