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Article

Angiotensin-converting enzyme DD genotype and cardiovascular disease in heterozygous familial hypercholesterolemia.

Circulation - 12 May 1998

O'Malley J P, Maslen C L, Illingworth D R

Abstract excerpt

BACKGROUND: Controversy exists as to whether the deletion/deletion genotype (DD) of the ACE gene polymorphism increases the risk of myocardial infarction (MI). Studies have suggested that the ACE DD genotype is associated with increased plaque instability. We hypothesized that the ACE DD genotype...

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Source

Identifiers

PMID: 9603531
DOI: 10.1161/01.cir.97.18.1780

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-9603531-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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Angiotensin-converting enzyme DD genotype and cardiovascular disease in heterozygous familial hypercholesterolemia.PMID 9603531Read ↗

Angiotensin-I converting enzyme genotype DD is a risk factor for coronary artery disease.Semantic proximity Read ↗

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Angiotensin-I-converting enzyme DD genotype is a risk factor of coronary artery disease.Semantic proximity Read ↗

A DNA variant at the angiotensin-converting enzyme gene locus associates with coronary artery disease in the Caerphilly Heart Study.Semantic proximity Read ↗

Hypothesis: an angiotensin converting enzyme genotype, present in one in three caucasians, is associated with increased mortality rate.Semantic proximity Read ↗

The DD-ACE genotype and cardiovascular disease.Semantic proximity Read ↗

Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction.Semantic proximity Read ↗

Renin-angiotensin system polymorphisms and coronary events in familial hypercholesterolemia.Semantic proximity Read ↗

DD genotype of the angiotensin-converting enzyme gene is a risk factor for left ventricular hypertrophy.Semantic proximity Read ↗

Interactions between angiotensin-I converting enzyme insertion/deletion polymorphism and response of plasma lipids and coronary atherosclerosis to treatment with fluvastatin: the lipoprotein and coronary atherosclerosis study.Semantic proximity Read ↗

Angiotensin-converting enzyme insertion/deletion genotype is associated with the activities of plasma coagulation factor VII and X independent of triglyceride metabolism.Semantic proximity Read ↗

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