Article
The DD-ACE genotype and cardiovascular disease.
Pharmacogenomics - 1 May 2000
Butler R
Abstract excerpt
The renin-angiotensin-aldosterone system (RAS) plays a pivotal role in the cardiovascular system, and the therapeutic agents which interact with this pathway have a significant impact in both heart failure and following myocardial infarction (MI). Polymorphisms within the genes controlling this enzyme system may also contribute to the pathogenesis of cardiovascular disease. Over the last decade an association...
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