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Article

Hypothesis: an angiotensin converting enzyme genotype, present in one in three caucasians, is associated with increased mortality rate.

Clinical and experimental pharmacology & physiology - 1 Jan 1996

Morris B J

Abstract excerpt

1. This review argues that the deletion (D) allele of an insertion (I)/deletion polymorphism of the angiotensin I-converting enzyme (ACE) gene is a marker for a variant associated with increased ACE expression, as well as myocardial infarction (MI) and other life-threatening conditions. 2. By exa...

Topics

Adult
Aged
Cardiovascular Diseases
Genotype
Humans
Middle Aged
Peptidyl-Dipeptidase A
Risk Factors

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8713489

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8713489-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Hypothesis: an angiotensin converting enzyme genotype, present in one in three caucasians, is associated with increased mortality rate.PMID 8713489Read ↗

Angiotensin I-converting enzyme insertion/deletion polymorphism: clinical implications.Semantic proximity Read ↗

Insertion/deletion polymorphism in the angiotensin-converting enzyme gene and risk of and prognosis after myocardial infarction.Semantic proximity Read ↗

Deletion polymorphism of the angiotensin I-converting enzyme gene is associated with increased plasma angiotensin-converting enzyme activity but not with increased risk for myocardial infarction and coronary artery disease.Semantic proximity Read ↗

Angiotensin-converting enzyme insertion/deletion polymorphism and risk of myocardial infarction in an updated meta-analysis based on 34993 participants.Semantic proximity Read ↗

Angiotensin-I converting enzyme genotype DD is a risk factor for coronary artery disease.Semantic proximity Read ↗

Angiotensin-converting enzyme gene deletion allele increases the risk of left ventricular hypertrophy: evidence from a meta-analysis.Semantic proximity Read ↗

DD genotype of the angiotensin-converting enzyme gene is a risk factor for left ventricular hypertrophy.Semantic proximity Read ↗

[ACE gene polymorphism and cardiovascular diseases].Semantic proximity Read ↗

ACE I/D gene polymorphism: presence of the ACE D allele increases the risk of coronary artery disease in younger individuals.Semantic proximity Read ↗

Association between angiotensin-converting enzyme insertion/deletion polymorphisms and the risk of heart disease: an updated meta-analysis.Semantic proximity Read ↗

Large-scale test of hypothesised associations between the angiotensin-converting-enzyme insertion/deletion polymorphism and myocardial infarction in about 5000 cases and 6000 controls. International Studies of Infarct Survival (ISIS) Collaborators.Semantic proximity Read ↗

The deletion/insertion polymorphism of the angiotensin converting enzyme gene and cardiovascular-renal risk.Semantic proximity Read ↗

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