Article
Hypothesis: an angiotensin converting enzyme genotype, present in one in three caucasians, is associated with increased mortality rate.
Clinical and experimental pharmacology & physiology - 1 Jan 1996
Morris B J
Abstract excerpt
1. This review argues that the deletion (D) allele of an insertion (I)/deletion polymorphism of the angiotensin I-converting enzyme (ACE) gene is a marker for a variant associated with increased ACE expression, as well as myocardial infarction (MI) and other life-threatening conditions. 2. By examination of I/D frequency in different age groups of individuals having well-known risk factors, it appears that...
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