Article
Renin-angiotensin system polymorphisms and coronary events in familial hypercholesterolemia.
Hypertension (Dallas, Tex. : 1979) - 1 Nov 2000
Wierzbicki A S, Lambert-Hammill M, Lumb P J, Crook M A
Abstract excerpt
The role of renin-angiotensin system polymorphisms as risk factors for coronary heart disease (CHD) is controversial. This study investigated their role in patients with heterozygous familial hypercholesterolemia (FH). Polymorphism frequencies for angiotensin-I-converting enzyme insertion/deletion (ACE I/D), angiotensinogen M235T, and angiotensin-II type I receptor (AG2R) A1166C were determined in 112 patients...
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