Article
Angiotensin-converting enzyme insertion/deletion genotype is associated with the activities of plasma coagulation factor VII and X independent of triglyceride metabolism.
Coronary artery disease - 1 Jun 2003
Okura Yoshifumi, Hayashi Kozo, Shingu Tetsuji, Kuga Yoshio, Nomura Shuichi, Kajiyama Goro, Nakashima Yoshiyuki, Saku Keijiro
Abstract excerpt
BACKGROUND: The D allele of angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism and coagulation activity play important roles in cardiovascular events, however, the precise association between these two risk factors remains unclear. METHODS: We identified the ACE I/D genotype and measured the plasma coagulation factor VII and X (FVII and FX) activities and serum lipids in 172 patients (110...
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