Article
Crystal structure of a mutant human lysozyme with a substituted disulfide bond.
Proteins - 1 Jun 2001
Inaka K, Kanaya E, Kikuchi M, Miki K
Abstract excerpt
The three-dimensional structure of a mutant human lysozyme, W64CC65A, in which a non-native disulfide bond Cys64--Cys81 is substituted for the Cys65--Cys81 of the wild type protein by replacing Trp64 and Cys65 with Cys and Ala, respectively, was determined by X-ray crystallography and refined to an R-value of 0.181, using 33,187 reflections at 1.87-A resolution. The refined model of the W64CC65A protein consisted...
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