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Article

Apolipoprotein E epsilon4 allele and progression of cortical Lewy body pathology in Parkinson's disease.

Acta neuropathologica - 1 May 1998

Wakabayashi K, Kakita A, Hayashi S, Okuizumi K, Onodera O, Tanaka H, Ishikawa A, Tsuji S, Takahashi H

Abstract excerpt

To elucidate whether the apolipoprotein E epsilon4 allele (APOE4) affects cortical neuropathology in Parkinson's disease (PD), we determined APOE genotypes and quantified the densities of cortical Lewy bodies (LBs), amyloid plaques and neurofibrillary tangles in 22 autopsy-proven PD cases (12 with dementia; 10 without dementia) that were not accompanied by Alzheimer's disease. The APOE4 frequency in the demented...

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Source

Identifiers

PMID: 9600590
DOI: 10.1007/s004010050824

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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