Article
Apolipoprotein E genotype as a risk factor for susceptibility to and dementia in Parkinson's disease.
Journal of neurology - 1 Mar 2009
Williams-Gray Caroline H, Goris An, Saiki Misuzu, Foltynie Thomas, Compston D Alastair S, Sawcer Stephen J, Barker Roger A
Abstract excerpt
Further to the well-established association between apolipoprotein E (APOE) and Alzheimer's disease, this gene has also been implicated in both susceptibility to, and dementia in, Parkinson's disease (PD). However studies to date have produced contradictory findings. We conducted a case-control s...
Topics
- Apolipoprotein E2
- Apolipoprotein E4
- Apolipoproteins E
- Case-Control Studies
- Cognition Disorders
- Dementia
- Female
- Follow-Up Studies
- Gene Frequency
- Genetic Predisposition to Disease
- Humans
- Male
- Middle Aged
- Neuropsychological Tests
- Odds Ratio
- Parkinson Disease
- Risk Factors
- Sequence Analysis, DNA