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Article

Inoculum composition and Salmonella pathogenicity island 1 regulate M-cell invasion and epithelial destruction by Salmonella typhimurium.

Infection and immunity - 1 Feb 1998

Clark M A, Hirst B H, Jepson M A

Abstract excerpt

In the mouse model of Salmonella typhimurium infection, the specialized antigen-sampling intestinal M cells are the primary route of Salmonella invasion during the early stages of infection. Under certain experimental conditions, M-cell invasion is accompanied by M-cell destruction and loss of adjacent regions of the follicle-associated epithelium (FAE), although the conditions responsible for expression of the...

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Identifiers

PMID: 9453633
DOI: 10.1128/IAI.66.2.724-731.1998
PMCID: PMC107963

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