Article
The Yersinia pestis Ail protein mediates binding and Yop delivery to host cells required for plague virulence.
Infection and immunity - 1 Feb 2009
Felek Suleyman, Krukonis Eric S
Abstract excerpt
Although adhesion to host cells is a critical step in the delivery of cytotoxic Yop proteins by Yersinia pestis, the mechanism has not been defined. To identify adhesins critical for Yop delivery, we initiated two transposon mutagenesis screens using the mariner transposon. To avoid redundant cell binding activities, we initiated the screen with a strain deleted for two known adhesins, pH 6 antigen and the...
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