Article
Relationship of p53 alteration and myc family gene overexpression with the clinical characteristics of lung cancer.
Chinese medical journal - 1 Apr 1997
Bai L, Sun Y, Li S
Abstract excerpt
OBJECTIVE: To evaluate the relationship of p53 alteration and myc family gene overexpression with the clinical characteristics of lung cancer. METHODS: A series of 59 resected primary lung cancer specimens was analyzed for p53 gene by DNA/PCR sequencing and immunohistochemistry technique, and for myc family genes by RT-PCR methods. RESULTS: Thirty-seven of 57 tumors were found to have p53 mutations or/and p53...
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