[Genetic alteration of lung cancer as a prognostic marker and its therapeutic implications].

Article

[Genetic alteration of lung cancer as a prognostic marker and its therapeutic implications].

Gan to kagaku ryoho. Cancer & chemotherapy - 1 Oct 1997

Mitsudomi T, Takahashi T

Abstract excerpt

Many genetic lesions found in non-small cell lung cancer (NSCLC) have been reported to be associated with a poor prognostic outcome of this disease. Such alterations include mutations of ras genes, overexpression of myc or erbB2 genes and inactivation of RB genes. Among them, the prognostic impli...

Topics

Adenocarcinoma
Carcinoma, Non-Small-Cell Lung
Carcinoma, Squamous Cell
Genes, p53
Humans
Lung Neoplasms
Mutation
Prognosis
Proportional Hazards Models
Retrospective Studies

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