Article
Co-operative effect of c-Src and ezrin in deregulation of cell-cell contacts and scattering of mammary carcinoma cells.
Journal of cellular biochemistry - 1 May 2004
Elliott Bruce E, Qiao Hui, Louvard Daniel, Arpin Monique
Abstract excerpt
The non-receptor tyrosine kinase c-Src is activated in many human cancer types, and induces deregulation of cadherin-based cell-cell contacts and actin cytoskeleton. Because ezrin, a protein which cross-links the plasma membrane with the actin cytoskeleton, is often over-expressed in human cancer...
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