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Article

Rescue of the mutant phenotype by reexpression of full-length vinculin in null F9 cells; effects on cell locomotion by domain deleted vinculin.

Journal of cell science - 1 Jun 1998

Xu W, Coll J L, Adamson E D

Abstract excerpt

Vinculin plays a role in signaling between integrins and the actin cytoskeleton. We reported earlier that F9-derived cells lacking vinculin are less spread, less adhesive, and move two times faster than wild-type F9 cells. Expression of intact vinculin in null cells restored all wild-type charact...

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Cell Line
Cell Movement
Microscopy, Confocal
Mutation
Transfection

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 9580561
DOI: 10.1242/jcs.111.11.1535

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-9580561-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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Rescue of the mutant phenotype by reexpression of full-length vinculin in null F9 cells; effects on cell locomotion by domain deleted vinculin.PMID 9580561Read ↗

Mechano-coupling and regulation of contractility by the vinculin tail domain.Semantic proximity Read ↗

Vinculin E29R mutation changes cellular mechanics.Semantic proximity Read ↗

Expression of chicken vinculin complements the adhesion-defective phenotype of a mutant mouse F9 embryonal carcinoma cell.Semantic proximity Read ↗

Vinculin organises apical Transcellular Actin Fibres to coordinate collective migrationSemantic proximity Read ↗

Vinculin regulates the recruitment and release of core focal adhesion proteins in a force-dependent manner.Semantic proximity Read ↗

Vinculin gene is non-essential in Drosophila melanogaster.Semantic proximity Read ↗

Role of vinculin in regulating focal adhesion turnover.Semantic proximity Read ↗

Vinculin functions as regulator of chondrogenesis.Semantic proximity Read ↗

Two distinct head-tail interfaces cooperate to suppress activation of vinculin by talin.Semantic proximity Read ↗

Suppression of vinculin expression by antisense transfection confers changes in cell morphology, motility, and anchorage-dependent growth of 3T3 cells.Semantic proximity Read ↗

Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility.Semantic proximity Read ↗

Integrin-mediated internalization of Staphylococcus aureus does not require vinculinSemantic proximity Read ↗

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