Article
Suppression of vinculin expression by antisense transfection confers changes in cell morphology, motility, and anchorage-dependent growth of 3T3 cells.
The Journal of cell biology - 1 Sept 1993
Rodríguez Fernández J L, Geiger B, Salomon D, Ben-Ze'ev A
Abstract excerpt
The expression of vinculin, a major component of adhesion plaques and cell-cell junctions, is markedly modulated in cells during growth activation, differentiation, motility and cell transformation. The stimulation of quiescent cells by serum factors and the culturing of cells on highly adhesive...
Topics
- 3T3 Cells
- Animals
- Cell Adhesion
- Cell Division
- Cell Movement
- DNA, Antisense
- Down-Regulation
- Fibroblasts
- Gene Expression
- Mice
- Mice, Inbred BALB C
- Phenotype
- Transcription, Genetic
- Transfection
- Vinculin