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Article

Normal human melanocytes that express a bFGF transgene still require exogenous bFGF for growth in vitro.

The Journal of investigative dermatology - 1 May 1998

Coleman A B, Lugo T G

Abstract excerpt

The expression of basic fibroblast growth factor (bFGF) has been implicated as an important factor in the development of malignant melanoma. The timing of this expression suggests that bFGF plays a role early in melanoma tumor progression. Benign nevi produce bFGF, and cells cultured from these lesions show a loss of dependence on exogenous bFGF for growth. We have examined the effects of constitutive bFGF...

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Identifiers

PMID: 9579548
DOI: 10.1046/j.1523-1747.1998.00166.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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