Article
Fibroblast growth factor-binding protein expression changes with disease progression in clinical and experimental human squamous epithelium.
International journal of cancer - 1 May 2001
Sauter E R, Nesbit M, Tichansky D, Liu Z J, Shirakawa T, Palazzo J, Herlyn M
Abstract excerpt
Basic fibroblast growth factor (bFGF) is synthesized by a wide variety of normal and malignant cells. However, bFGF cannot exert its effects unless it gets outside of the cell. Since it lacks a signal sequence to direct secretion, the method by which cells release it remains unclear. A 17 kDa sec...
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