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Article

Cytokines in human melanoma cells: synthesis, autocrine stimulation and regulatory functions--an overview.

Melanoma research - 1 Dec 1993

Krasagakis K, Garbe C, Orfanos C E

Abstract excerpt

Various cytokines are involved in growth regulation of human melanoma cells. Malignant melanoma cells express multiple growth factors, including basic fibroblast growth factor (bFGF), transforming growth factor (TGF)-alpha, platelet-derived growth factor (PDGF)-alpha, and melanoma growth stimulatory activity (MGSA), substances which are not expressed in normal human melanocytes. The simultaneous synthesis of...

Topics

Antigens, Neoplasm
Cell Division
Cytokines
Gene Expression Regulation, Neoplastic
Growth Substances
Humans
Melanoma
Neoplasm Proteins
Phenotype
Receptors, Cytokine
Receptors, Growth Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8161882

Genes

EGF
NGF
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8161882-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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