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Article

Overexpression of p53 protein in cutaneous T cell lymphoma: relationship to large cell transformation and disease progression.

The Journal of investigative dermatology - 1 May 1998

Li G, Chooback L, Wolfe J T, Rook A H, Felix C A, Lessin S R, Salhany K E

Abstract excerpt

The molecular mechanisms by which advanced cases of cutaneous T cell lymphoma (CTCL) (mycosis fungoides/Sezary syndrome) undergo large cell transformation (LCT) and develop the morphologic appearance of a large cell lymphoma, are undefined. We used immunohistochemical analysis and polymerase chain reaction/single strand conformational polymorphism to examine whether p53 mutations are associated with disease...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9579543
DOI: 10.1046/j.1523-1747.1998.00167.x

Genes

LCT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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