Article
Genotypic analysis of T-cell clones derived from cutaneous T-cell lymphoma lesions demonstrates selective growth of tumor-infiltrating lymphocytes.
The Journal of investigative dermatology - 1 Jul 1990
Ho V C, Baadsgaard O, Elder J T, Hansen E R, Hanson C A, Vejlsgaard G L, Cooper K D
Abstract excerpt
The nature of T cells contained within cutaneous lesions of cutaneous T-cell lymphoma (CTCL) has not been studied at the clonal level. T cells extracted from skin lesions of two CTCL patients were cloned by limiting dilution and propagated in interleukin-2 (IL-2) containing medium with periodic l...
Topics
- Cell Division
- Clone Cells
- Gene Rearrangement
- Genotype
- Humans
- Lymphoma
- Receptors, Antigen, T-Cell
- Receptors, Antigen, T-Cell, alpha-beta
- Receptors, Antigen, T-Cell, gamma-delta
- Skin
- Skin Neoplasms
