Article
Genotypic analysis of cutaneous T-cell lymphoma: a comparative study of Southern blot analysis with polymerase chain reaction amplification of the T-cell receptor-gamma gene.
The British journal of dermatology - 1 Nov 1997
Curcó N, Servitje O, Llucià M, Bertran J, Limón A, Carmona M, Romagosa V, Peyrí J
Abstract excerpt
The diagnosis of early cutaneous T-cell lymphoma (CTCL) is a difficult point in dermatology. Recently, Southern blot analysis (SBA) and polymerase chain reaction (PCR) have been used to detect clonality in initial lesions in which clinical and histological findings are unspecific. Forty-one sampl...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Blotting, Southern
- DNA Primers
- Electrophoresis, Polyacrylamide Gel
- Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor
- Genotype
- Humans
- Lymphoma, T-Cell, Cutaneous
- Middle Aged
- Mycosis Fungoides
- Polymerase Chain Reaction