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Article

Genetic influence on disease course and cytokine response in relapsing experimental allergic encephalomyelitis.

International immunology - 1 Mar 1998

Kjellén P, Issazadeh S, Olsson T, Holmdahl R

Abstract excerpt

A protracted and relapsing form of experimental allergic encephalomyelitis (EAE) develops in the DA rat after immunization with rat spinal cord homogenate (SCH) emulsified in incomplete Freund's adjuvant (IFA). The genetic influence on this model has been analyzed by immunizing MHC congenic strains on both LEW and DA genetic backgrounds, and recombinant inbred strains between DA and E3 rats. An in situ...

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PMID: 9576621
DOI: 10.1093/intimm/10.3.333

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MBP

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