Genetic influence on disease course and cytokine response in relapsing experimental allergic encephalomyelitis.

doi:10.1093/intimm/10.3.333

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Article

Genetic influence on disease course and cytokine response in relapsing experimental allergic encephalomyelitis.

International immunology - 1 Mar 1998

Kjellén P, Issazadeh S, Olsson T, Holmdahl R

Abstract excerpt

A protracted and relapsing form of experimental allergic encephalomyelitis (EAE) develops in the DA rat after immunization with rat spinal cord homogenate (SCH) emulsified in incomplete Freund's adjuvant (IFA). The genetic influence on this model has been analyzed by immunizing MHC congenic strai...

Topics

Amino Acid Sequence
Animals
Cytokines
Encephalomyelitis, Autoimmune, Experimental
Genetic Predisposition to Disease
Molecular Sequence Data
Myelin Basic Protein
RNA, Messenger
Rats
Rats, Inbred Lew
Spinal Cord

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