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Article

Multiple loci comprising immune-related genes regulate experimental neuroinflammation.

Genes and immunity - 1 Jan 2010

Marta M, Stridh P, Becanovic K, Gillett A, Ockinger J, Lorentzen J C, Jagodic M, Olsson T

Abstract excerpt

A 58 Mb region on rat chromosome 4 known to regulate experimental autoimmune encephalomyelitis (EAE) was genetically dissected. High-resolution linkage analysis in an advanced intercross line (AIL) revealed four quantitative trait loci (QTLs), Eae24-Eae27. Both Eae24 and Eae25 regulated susceptibility and severity phenotypes, whereas Eae26 regulated severity and Eae27 regulated susceptibility. Analyses of the...

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Share to Immunoglobulin G
Share to Encephalomyelitis, Autoimmune, Experimental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Myelin-Associated Glycoprotein

Share to Myelin-Oligodendrocyte Glycoprotein

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Source

Identifiers

PMID: 19675581
DOI: 10.1038/gene.2009.62

Genes

MOG

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